Pulmonary Embolism Due to Protein S Deficiency in Pregnancy

Pulmonary embolism in pregnancy.

Pulmonary embolism (PE) is the leading cause of maternal mortality in the developed world. Mortality from PE in pregnancy might be related to challenges in targeting the right population for prevention, ensuring that diagnosis is suspected and adequately investigated, and initiating timely and best possible treatment of this disease. Pregnancy is an example of Virchow's triad: hypercoagulabilit...

Massive pulmonary embolism arising from a bifid ovarian vein in a patient with protein S deficiency.

A 36 year-old woman was admitted to the intensive care unit for sudden onset of dyspnea and near-syncope. She had resting tachypnea, tachycardia, blood pressure of 110/70 mm Hg and oxygen saturation of 90% on room air. There was no evidence of clinical thrombophlebitis of lower limbs. The ECG showed sinus tachycardia, incomplete right bundle branch block and non-specific T wave abnormalities. C...

Acute pulmonary embolism due to hydatid cysts.

Extrahepatic portal hypertension due to familial protein S deficiency.

Portal vein thrombosis (PVT) is a common cause of portal hypertension in children. A majority of children with PVT of unknown etiology have functional Protein C deficiency or abnormally elevated levels of anti-cardiolipin antibodies. We report an 8 years old Indian girl with portal cavernoma due to hereditary Protein S deficiency. We documented familial deficiency of Protein S in 2 asymptomatic...

Evaluation of suspected pulmonary embolism in pregnancy.

(b) bilateral CuS after a technically inadequate CtPa. A repeat CTPA should be performed only if a review of prior study suggests a technical cause that can be remedied or improved. A positive CUS may preclude the need for further tests that involve radiation. Consider repeating the CUS twice, on days 3 and 7. While serial ultrasound has not been directly studied in suspected PE, this strategy ...